Artemisinin Efficacy on iNOS Production in U937 Cell-line Infected with Leishmania donovani

Cancrum Oris in a Monkey Infected with Leishmania Donovani

The object of this note is to {Macaca rence of cancrum oris m a 0ccairus). It is believed that tins occlirred sion on which this compnca Leishin an experimental animal mie mania donovani. ? ... ^nnVey is that The previous history of thw . fectkm jn the ^ had been given a malaria g Napier scries of experiments reported necesand Campbell (1932) and that ai obtained, sary data regarding malaria ^ ...

Recombinant interleukin-1 alpha augments granuloma formation and cytokine production but not parasite clearance in mice infected with Leishmania donovani.

In vivo administration of various doses of recombinant interleukin-1 alpha to B10.D2/n mice chronically infected with Leishmania donovani resulted in enhanced formation of granulomas and in vitro production of gamma interferon. By direct microscopical enumeration, reduction in gross parasite burden in the viscera was not observed, however. These data highlight an important discordance between g...

Experimental chemotherapy with Allium sativum (Liliaceae) methanolic extract in rodents infected with Leishmania major and Leishmania donovani.

BACKGROUND & OBJECTIVES Several plant products have been tested and found to possess antileishmanial activity. The present study was undertaken to establish whether methanolic extract of Allium sativum Linn has antileishmanial activity in comparison to standard drugs. METHODS Methanolic extract of A. sativum bulbs was screened for in vitro and in vivo antileishmanial activity against Leishman...

On Transient Infections with Leishmania Donovani in Man and Animals

Parthenolide Induces Apoptosis in Committed Progenitor AML Cell line U937 via Reduction in Osteopontin

Background: Interfering with cell proliferation and survival is a critical role for antineoplastic drugs leading to cell death through induction of apoptosis. Alternative treatments with herbal extracts offer insights into acute myeloid leukemia (AML) therapy. Parthenolide (PTL), an extract from feverfew, induces apoptosis in primary human leukemia stem cells (LSCs) and bulk leukemic cell popul...